Signaling Breakthroughs of 2007
Science (or rather, the AAAS) is renaming its online “virtual journal” from Signal Transduction Knowledge Environment to Science Signaling, and they present their annual solicited opinions from researchers on the best cell signaling papers from 2007.
Some cool highlights include (of course) the breakthrough somatic cell reprogramming papers from this year in humans (which are followups to the papers in mouse a year ago), but also the discovery of an acetylation cascade in interferon signaling, a feedforward amplification circuit in innate immunity signaling during viral infection by the creation of short RNAs, the elucidation of the mechanism of the cyanobacterial circadian Kai oscillator, and the discovery of the “cold” temperature receptor in mammals.
Check out the entire list at Science Signaling!